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Rhabdomyosarcoma

A rhabdomyosarcoma is a type of cancer, specifically a sarcoma (cancer of connective tissues), in which the cancer cells are thought to arise from skeletal muscle progenitors. It can also be found attached to muscle tissue, wrapped around intestines, or anywhere, to include the neck area. It is most common in children ages one to five, and teens aged 15 to 19, although quite rare in the latter.

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Projects.

Projects

P1: Titin based mechanotransduction in skeletal muscle atrophy and hypertrophy

P2: Muscle and fat tissue wasting in patients with chronic heart failure: the impact of impaired insulin sensitivity

P3: Skeletal muscle metabolism and critical illness myopathy during early course of systemic inflammation

P4: Analysis of nucleocytoplasmic transport in muscle disorders caused by mutations in lamins A/C

P6: Regulation of myostatin in dysferlin-deficient muscular dystrophy

P7: Influence of myostatin (GDF8) and follistatin on in vitro and in vivo rhabdomyosarcoma differentiation and growth

P8: The functional role of ahnak in skeletal muscle fibers in an ahnak knock-out mouse model

P9: Skeletal muscle metabolism in patients with lamin A/C-dependent familial partial lipodystophy

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